EMRP Project "Metrology for Metalloproteins" - HLT05



Metalloproteins are especially important in medical diagnosis as they represent around 30 % of the whole proteom. Many of them such as haemoglobin (Hb), transferrin (Tf), superoxide dismutase (SOD) or ceruloplasmin (Cp) are important markers for diseases such as Down’s syndrome in the prenatal diagnostic (SOD), inflammation (acute-phase proteins like Tf or C-reactive protein (CRP)) or deficiency diseases (Hb, Tf, Cp). Moreover, they are used for the control of treatment efficiency e.g. total Hb as the most important marker for anaemia treatment. Other metalloproteins are important in cancer treatment like selenoproteins or platinum (Pt) containing drugs that form adducts to biomolecules.


Opens internal link in current windowMetrology Workshop at EWCPS in Münster 2015-02-24