Metabolic imaging at high and very high fields: from systems architecture to application

Magnetic resonance spectroscopy rapidly evolved during the last 10 years and today allows for in vivo detection of more than 20 metabolites and compounds, their concentration changes over time as well as assessment of metabolic turnover rates. A comprehensive overview about most recent MR spectroscopy methodology established by my research group is given as well as applications in the areas of biological psychiatry, neurology and cardiology. Finally recent advances in enabling technology for ultra-high field metabolic imaging including B0 shimming, parallel transmission and RF coil design are presented.