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Article
| Title: | Latency analysis of single auditory evoked M100 responses by spatio-temporal filtering |
|---|---|
| Author(s): | G. Wübbeler, A. Link, M. Burghoff, L. Trahms and C. Elster |
| Journal: | Physics in medicine and biology |
| Year: | 2007 |
| Volume: | 52 |
| Issue: | 15 |
| Pages: | 4383--92 |
| DOI: | 10.1088/0031-9155/52/15/002 |
| ISSN: | 0031-9155 |
| Web URL: | http://www.ncbi.nlm.nih.gov/pubmed/17634639 |
| Keywords: | Acoustic Stimulation,Acoustic Stimulation: methods,Algorithms,Diagnosis, Computer-Assisted,Diagnosis, Computer-Assisted: methods,Evoked Potentials, Auditory,Evoked Potentials, Auditory: physiology,Humans,Magnetoencephalography,Magnetoencephalography: methods,Pitch Perception,Pitch Perception: physiology,Reaction Time,Reaction Time: physiology,Reproducibility of Results,Sensitivity and Specificity |
| Tags: | 8.42, Gehirn |
| Abstract: | Appropriate spatial filtering followed by temporal filtering is well suited for the single-trial analysis of multi-channel magnetoencephalogram or electroencephalogram recordings. This is demonstrated by the results of a single-trial latency analysis obtained for auditory evoked M100 responses from nine subjects using two different stimulation frequencies. Spatial filters were derived automatically from the data via noise-adjusted principle component analysis, and single-trial latencies were estimated from the signal phase after complex bandpass filtering. For each of the two stimulation frequencies, estimated single-trial latencies were consistent with results obtained from a standard approach using averaged evoked responses. The quality of the estimated single-trial latencies was additionally assessed by their ability to separate between the two different stimulation frequencies. As a result, more than 80% of the single trials can be classified correctly by their estimated latencies. |