3D model-based super-resolution motion-corrected cardiac T1-mapping

Simone Hufnagel (PTB), together with Selma Metzner (PTB), Kirsten Kerkering (PTB), Christoph Aigner (PTB), Andreas Kofler (PTB), Jeanette Schulz-Menger (Charité), Tobias Schäffter (PTB) and Christoph Kolbitsch (PTB ) published an article on a method for generating high-resolution MRI T1-maps of the heart.

One of the major challenges in cardiac T1-mapping is that the achievable image resolution is often limited due to respiratory and cardiac motion, SNR and limited acquisition time. In clinical practice, usually one 2D-slice is acquired per breath hold, which has high in-plane resolution but suffers from poor in-plane resolution of 6-8 mm. In this article, a model-based super-resolution reconstruction approach for cardiac T1-mapping is presented, which provides precise high-resolution 3D-T1-maps with improved visualization of small structures compared to the acquired images. The approach combined multiple stacks of 2D-acquisitions with slice thicknesses of 6 to 8 mm and generated 3D-high-resolution T1-maps with a target slice thickness of 1.5 to 2 mm in six to ten breath-hold states.

This work has now been published in Physics in Medicine and Biology (doi: 10.1088/1361-6560/ac9c40)

Contact:

Simone Hufnagel, E-Mail: Simone.Hufnagel(at)ptb.de