Proof of SARS-CoV-2 infection is based on detection of genetic markers - e.g. using PCR. The infection can also be proved by detection of characteristic proteins. Antigen tests make use of this approach. We tested the correlation between genetic markers and proteins of SARS-CoV-2. Two quantitative methods were used. The gene concentration was measured using digital PCR. This method provides most...
In response to the high demand for rapid SARS-CoV-2 diagnostic tests, lateral flow tests have been widely used as a diagnostic tool to detect SARS-CoV-2 antigens. Compared to PCR tests, these tests are inexpensive to produce and easy to use. They provide a rapid visual result and are ideal for point-of-care settings.
When a real measurement procedure is reproduced by simulations, it may be referred to as a “virtual measurement”. From a metrological point of view, the question is how to ensure confidence in such virtual measurements. While methods to estimate diverse sources of error in simulations have been developed over the past decades, there has to date been no accepted strategy for meeting the...Archive of Annual Reports
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