Standardized technical validation of biophotonic devices is indispensable for the reliability and reproducibility of measurement results in their medical use. This requires suitable standardized phantoms, i.e., tissue-like test specimens, and recognized standards for evaluating the performance of these devices. Both prerequisites are not sufficiently met in the field of medical optical imaging. A...
[ more ]
Contrast-agent based fluorescence imaging offers a unique potential for early diagnosis and therapy of rheumatic diseases. 3D printing of fluorescent phantoms with Lumogen IR 765 is a promising method for producing anatomically shaped tissue models of high stability. 
Xenon noble gas atoms can form transient complexes with host molecules in solution. The resulting host-guest systems are held together by non-covalent bonds. They are an example of supramolecular systems. They may thus serve for the analysis of similar chemical or pharmaceutical carrier and delivery systems. Xenon complexation is currently also explored as potential contrast agent in magnetic...
PCR tests were used already at the beginning of the covid-19 pandemic. SARS-CoV-2 is an RNA virus. However, PCR can only detect DNA. Therefore, RNA is first transcribed into DNA. Next the DNA is specifically amplified. A high viral concentration generates a strong signal. This allows to use a PCR test to detect or exclude an infection by SARS-CoV-2. The analytical sensitivity of PCR tests can vary...