Profile
The working group carries out research and development on non-invasive methods for medical diagnostics and monitoring of therapy in the fields of biomedical optics. The work is focused on methods for quantitative measurement of the distribution of important biomarkers in living tissue like hemoglobin concentration and blood oxygen saturation, and on methods for the detection of fluorescence signals emitted by labeled cells ex vivo or by contrast agents and molecular probes in vivo. The group develops optical spectroscopic imaging techniques that are tested on tissue equivalent phantoms as well as in clinical and preclinical studies. Moreover, algorithms are developed that enable quantification of tissue optical properties and biomarker concentrations in vivo and cell concentrations ex vivo.
Research/Development
In vivo optical imaging and spectroscopy
Cerebral oximetry - reference measurement procedures and performance characterization
Characterization of renal haemodynamics and oxygenation by near-infrared spectroscopy
Quantitative fluorescence imaging
Fluorescence imaging of perfusion alterations for the detection of rheumatoid diseases
Fluorescence guided detection of sentinel lymph nodes
Calibration
