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Biomedical Magnetic Resonance

Department 8.1

Tasks

The department engages in method development for magnetic resonance imaging (MRI) and spectroscopy (MRS).

Specific methodological aspects of MRI are covered by currently three research groups: physical basics and safety (8.11), data acquisition and image reconstruction algorithms for motion correction and multimodal imaging (8.13), excitation and acquisition techniques specifically designed to harvest the potential of 'ultrahigh' (7T) magnetic fields (8.14).
Central research tool is a whole-body 3-tesla MR scanner. Additionally, the department is engaged in the Berlin Ultrahigh Field Facility which is operating a 7-tesla whole body scanner.

News

Ultra-high field MRI (UHF; ≥ 7 Tesla) unlocks superior resolution and contrast for studying the central nervous system (CNS) compared to lower field strengths. This makes 7-T-MRI highly valuable for investigating the spinal cord's role in neurological diseases. However, the spinal cord's thin, elongated shape and position within the spine present significant challenges for achieving high-quality...

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In quantitative MRI imaging of the heart, one is often limited to two-dimensional parameter maps with large slice thicknesses due to the low signal-to-noise ratio together with cardiac motion. Simone Hufnagel and coworkers from PTB's Quantitative MRI group 8.13 have now developed a method that allows the acquisition of three-dimensional T1 maps of the entire heart –including the...

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The separate imaging of fat and water rich tissue is a frequent objective in magnetic resonance imaging (MRI). An efficient solution is provided by the Dixon technique where both compartments are excited simultaneously and the signals are later separated based on their different temporal evolution. At the 'ultrahigh' MRI field strength of 7T, the frequency shift between fat and water protons is...

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