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Counting different blood cell types simultaneously

PTB-News 3.2017
Especially interesting for

medical engineering



The quantitative investigation of cells in blood by means of flow cytometry is a routine procedure in medical diagnostics. Thanks to the development of this novel procedure by PTB, it has become possible to determine the concentrations of erythrocytes, thrombocytes and leukocytes in blood samples simultaneously and reliably by means of AC impedance.

Mikrofluidische Baugruppe mit Flusskanal (Mitte) und Sensorelektroden.

Due to this, hemolysis, which might destroy target cells in patients with diseases, can be avoided. Via a micro-channel system with hydrodynamic focusing, the blood sample is led to a sensor which measures the electric impedance (typically in a range from 1 MHz to 10 MHz). It is thus possible for the first time to determine concentrations easily and reliably by impedance measurements without staining or hemolysis in patients with diseases such as leukemia. (Technology Offer 0422)


no hemolysis

no (fluorescence) staining required

improved diagnosis of leukemia and anemia

low cost

Contact person for questions about technology transfer

Andreas Barthel,
Phone: +49 (0)531 592-8307,
Opens window for sending emailandreas.barthel(at)ptb.de,
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