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Working Group 8.21

Development of bioelectric and biomagnetic measurement methods for medical diagnostics



  • Development of bioelectric and biomagnetic measurement procedures

    Physical phantoms with defined properties serve as reference systems in the development of new imaging modalities. A non-magnetic phantom manufactured by PTB allows to mimic the distribution of magnetic nanoparticles inside an organism. After magnetic excitation by the coil array (green) the signals of the nanoparticles are measured by the multi-channel SQUID system visible on the top. Mathematical models in the evaluation software allow the reconstruction of the nanoparticle distribution in the investigated object.
  • Magnetoencephalography (MEG)

    MEG is a non-invasive measurement procedure for the investigation of electrical activity of the human brain. SQUID sensors record the tiny biomagnetic signals produced by electrical currents from neuron populations in the brain. The helmet MEG system of PTB comprises 128 SQUID sensors arranged in a spherical geometry in order to catch activity from many patches of the cerebral cortex. MEG is employed together with Charité University Hospital and other partners for the development of biomagnetic equipment and procedures as well as neurologic and psychiatric diagnostics.

  • MEG with optically pumped magnetometers
    Optically pumped magnetometers (OPM) are developed as an alternative sensor system for recording of tiny magnetic fields. OPMs are based on the precession of unpaired electron couples in atomic gases (e.g. Rubidium). The Larmor frequency of the precession is directly proportional to the actual magnetic field strength.  OPMs can work without extensive cooling and have an working volume of a few cubic centimeters. The suitability of these sensors for biomagnetic applications is tested in the heavily magnetically shielded room BMSR-2.

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Die Arbeitsgruppe Biomagnetismus berät externe Wissenschaftler und Geräteentwickler zu allen Fragen der Messung körpereigener Magnetfelder.

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